Monosomy 21, partial duplication of chromosome 11, and structural abnormality of chromosome 1q21 in a case of lymphoma developing in a transplant recipient: characteristic abnormalities of secondary lymphoma?

F Cabanillas; S Pathak; A Zander; A Goodacre; R Katz; N Sneige; J Trujillo; A Cork; J Manning; J J Butler

doi:10.1016/0165-4608(87)90078-1

Monosomy 21, partial duplication of chromosome 11, and structural abnormality of chromosome 1q21 in a case of lymphoma developing in a transplant recipient: characteristic abnormalities of secondary lymphoma?

Cancer Genet Cytogenet. 1987 Jan;24(1):7-10. doi: 10.1016/0165-4608(87)90078-1.

Authors

F Cabanillas, S Pathak, A Zander, A Goodacre, R Katz, N Sneige, J Trujillo, A Cork, J Manning, J J Butler

PMID: 3539317
DOI: 10.1016/0165-4608(87)90078-1

Abstract

Cytogenetic analysis by QFQ-banding of direct preparation of a testicular mass from a patient with secondary lymphoma revealed a modal chromosome number of 45,XY, including structural and numerical anomalies. The most consistent anomalies were the monosomy 21, duplication of the long arm of #11, and structural anomaly associated with chromosome #1 in band q21.

Publication types

Case Reports

MeSH terms

Adult
Bone Marrow Transplantation*
Chromosome Aberrations*
Chromosome Banding
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 21
Humans
Karyotyping
Leukemia, Myeloid / pathology
Leukemia, Myeloid / therapy*
Lymphoma / genetics*
Lymphoma / pathology
Male
Monosomy
Multigene Family
Neoplasms, Multiple Primary / genetics
Neoplasms, Multiple Primary / pathology