New insights into the management of post-hemorrhagic hydrocephalus

Semin Perinatol. 2022 Aug;46(5):151597. doi: 10.1016/j.semperi.2022.151597. Epub 2022 Mar 12.

Abstract

During the last decade, an increasing number of studies have been conducted to improve the outcome of post-hemorrhagic hydrocephalus (PHH), a complication of severe intraventricular hemorrhage (IVH) in preterm infants. Two randomized controlled trials have shown that treatment should be initiated prior to the onset of clinical symptoms. Ventricular access devices and subgaleal shunts are used as temporary neurosurgical interventions whereas ventriculoperitoneal shunts are performed for infants with progressive hydrocephalus. Recently, techniques such as neuro-endoscopic lavage have also been introduced to eliminate toxic blood products and debris from the cerebral ventricles and have shown promise in early clinical studies. The objective of this review is to provide an update on management of PHVD and PHH in the preterm infant.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Hemorrhage / surgery
  • Cerebral Hemorrhage / therapy
  • Cerebral Ventricles
  • Humans
  • Hydrocephalus* / complications
  • Hydrocephalus* / therapy
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases*
  • Retrospective Studies