Pharmacist-administered audiology screening for pediatric cystic fibrosis patients exposed to high-dose aminoglycosides: A pilot study

Pediatr Pulmonol. 2022 Jul;57(7):1814-1817. doi: 10.1002/ppul.25946. Epub 2022 May 14.

Abstract

This pilot study successfully implemented a standardized protocol for tablet-based ototoxicity screening in pediatric cystic fibrosis (CF) patients exposed to aminoglycosides. Further studies are needed to assess the impact of implementation in a larger number of patients, as well as to determine barriers that may exist at centers with variation in available resources. This method of ototoxicity screening represents an accessible alternative to traditional audiology testing, and given the continued improvements in expected life span for people with CF, it is imperative that patients have regular access to this type of screening to allow for early identification of medication-related toxicities.

Keywords: aminoglycosides; audiology; cystic fibrosis; ototoxicity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Letter

MeSH terms

  • Aminoglycosides / adverse effects
  • Anti-Bacterial Agents / adverse effects
  • Audiology*
  • Child
  • Cystic Fibrosis* / drug therapy
  • Humans
  • Ototoxicity*
  • Pharmacists
  • Pilot Projects

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents