Mechanisms of Exercise-Induced Cardiac Remodeling Differ Between Young and Aged Hearts

Emily E Schmitt; Benjamin D McNair; Sydney M Polson; Ross F Cook; Danielle R Bruns

doi:10.1249/JES.0000000000000290

Mechanisms of Exercise-Induced Cardiac Remodeling Differ Between Young and Aged Hearts

Exerc Sport Sci Rev. 2022 Jul 1;50(3):137-144. doi: 10.1249/JES.0000000000000290. Epub 2022 May 5.

Authors

Emily E Schmitt, Benjamin D McNair¹, Sydney M Polson¹, Ross F Cook¹, Danielle R Bruns

Affiliation

¹ Division of Kinesiology & Health, University of Wyoming, Laramie, WY.

Abstract

Aging induces physiological and molecular changes in the heart that increase the risk for heart disease. Several of these changes are targetable by exercise. We hypothesize that the mechanisms by which exercise improves cardiac function in the aged heart differ from those in the young exercised heart.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aging / physiology
Heart
Humans
Myocardium*
Ventricular Remodeling* / physiology

Abstract

Publication types

MeSH terms

Grants and funding