Ketamine-induced uropathy: A diagnostic pitfall in an increasing healthcare issue in youngsters

Glenn Lamers; Johan Van Dyck; Stijn Schapmans; Katrien De Coster; Dries Mortier; Natalia Zabegalina

doi:10.1016/j.eucr.2022.102019

Ketamine-induced uropathy: A diagnostic pitfall in an increasing healthcare issue in youngsters

Urol Case Rep. 2022 Feb 1:42:102019. doi: 10.1016/j.eucr.2022.102019. eCollection 2022 May.

Authors

Glenn Lamers^{1

2}, Johan Van Dyck¹, Stijn Schapmans¹, Katrien De Coster¹, Dries Mortier³, Natalia Zabegalina¹

Affiliations

¹ Department of Urology, Maria Hospital North Limburg, Maesensveld 1, 3900, Pelt, Belgium.
² Department of Urology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
³ Department of Urology, AZ Vesalius, Hazelereik 51, 3700, Tongeren, Belgium.

Abstract

Ketamine induced uropathy (KIU) is a urological condition increasing in prevalence, with similar symptoms to UTI, OAB syndrome or interstitial cystitis/bladder pain syndrome. We present the case of an 18-year old male who established severe LUTS and acute kidney injury due to KIU, in a short time-span of 6 months. Since cessation of ketamine is the cornerstone of treating KIU, correct and early diagnosis is essential. Physicians should therefore consider KIU as a differential diagnosis in storage LUTS, especially in younger patients with therapy-resistant LUTS.

Keywords: ADHD, Attention-deficit/hyperactivity disorder; BPS, bladder pain syndrome; Bladder; CRP, C-reactive protein; IV, intravenous; KIU, ketamine induced uropathy; Ketamine; LUTS; LUTS, lower urinary tract symptoms; NMDA, N-Methyl-d-aspartate; STD, sexual transmitted disease; UTI, urinary tract infection; Uropathy; hpf, high power field.

Publication types

Case Reports