Feasibility of tumour-focused adaptive radiotherapy for bladder cancer on the MR-linac

A Mitchell; M Ingle; G Smith; J Chick; S Diamantopoulos; E Goodwin; T Herbert; R Huddart; H McNair; U Oelfke; S Nill; A Dunlop; S Hafeez

doi:10.1016/j.ctro.2022.04.008

Feasibility of tumour-focused adaptive radiotherapy for bladder cancer on the MR-linac

Clin Transl Radiat Oncol. 2022 Apr 26:35:27-32. doi: 10.1016/j.ctro.2022.04.008. eCollection 2022 Jul.

Authors

A Mitchell¹, M Ingle^{2

3}, G Smith³, J Chick¹, S Diamantopoulos¹, E Goodwin¹, T Herbert³, R Huddart^{2

3}, H McNair^{2

3}, U Oelfke¹, S Nill¹, A Dunlop¹, S Hafeez^{2

3}

Affiliations

¹ The Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.
² The Institute of Cancer Research, London, UK.
³ The Royal Marsden NHS Foundation Trust, London, UK.

Abstract

Bladder tumour-focused magnetic resonance image-guided adaptive radiotherapy using a 1.5 Tesla MR-linac is feasible. A full online workflow adapting to anatomy at each fraction is achievable in approximately 30 min. Intra-fraction bladder filling did not compromise target coverage with the class solution employed.

Keywords: Adaptive radiotherapy; Bladder cancer; MR-guided radiotherapy; MR-linac.

Abstract

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