Egg yolk sialylglycopeptide: purification, isolation and characterization of N-glycans from minor glycopeptide species

Org Biomol Chem. 2022 Jun 22;20(24):4905-4914. doi: 10.1039/d2ob00615d.

Abstract

Sialylglycopeptide (SGP) is a readily available naturally occurring glycopeptide obtained from hen egg yolk which is now commercially available. During SGP extraction, other minor glycopeptide species are identified, bearing N-glycan structures that might be of interest, such as asymmetrically branched and triantennary glycans. As the scale of SGP production increases, recovery of minor glycopeptides and their N-glycans can become more feasible. In this paper, we aim to provide structural characterization of the N-glycans derived from these minor glycopeptides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chickens*
  • Egg Yolk* / chemistry
  • Female
  • Glycopeptides / chemistry
  • Polysaccharides / chemistry

Substances

  • Glycopeptides
  • Polysaccharides