Crovalimab for treatment of patients with paroxysmal nocturnal haemoglobinuria and complement C5 polymorphism: Subanalysis of the phase 1/2 COMPOSER study

Br J Haematol. 2022 Aug;198(3):e46-e50. doi: 10.1111/bjh.18274. Epub 2022 May 24.
No abstract available

Keywords: C5 polymorphism; COMPOSER; anti-C5 inhibitor; crovalimab; paroxysmal nocturnal haemoglobinuria.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal* / therapeutic use
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Complement C5 / genetics
  • Hemoglobinuria, Paroxysmal* / drug therapy
  • Hemoglobinuria, Paroxysmal* / genetics
  • Humans

Substances

  • Antibodies, Monoclonal
  • Complement C5