Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy

Jeffrey Vehawn; Mouneeb Choudry; Jonathon Mahlow; Jayant Agarwal; Christopher Dechet; Alejandro Sanchez

doi:10.1016/j.eucr.2022.102120

Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy

Urol Case Rep. 2022 May 20:43:102120. doi: 10.1016/j.eucr.2022.102120. eCollection 2022 Jul.

Authors

Jeffrey Vehawn¹, Mouneeb Choudry¹, Jonathon Mahlow², Jayant Agarwal³, Christopher Dechet¹, Alejandro Sanchez¹

Affiliations

¹ Division of Urology, Department of Surgery, Huntsman Cancer Institute and University of Utah, Salt Lake City, UT, USA.
² Department of Pathology, University of Utah, Salt Lake City, UT, USA.
³ Division of Plastic Surgery, Department of Surgery, University of Utah, Salt Lake City, UT, USA.

Abstract

A 29-year-old patient presented to his primary care provider complaining of a painful right inguinal swelling. He was referred for inguinal hernia repair, but during surgery, an enlarged necrotic-appearing testicle was observed and removed. Pathology demonstrated a mixed non-seminomatous germ cell tumor (NSGCT) with evidence of tumor violation. After receiving BEPx3 for elevated post-operative AFP his tumor markers normalized. On surveillance, he was found to have several palpable masses around his inguinal incision. On soft tissue excision he was found to have residual teratoma within his soft tissues. We review the literature on germ cell tumor seeding and atypical recurrences.

Keywords: BEP, Bleomycin, etoposide, cisplatin; Cancer recurrence; NSGCT, Non-seminomatous germ cell tumor; STM, Serum tumor marker; Testicular germ cell tumor; Tumor seeding.

Publication types

Case Reports