In silico identification of Theileria parva surface proteins

Nitisha Gurav; Olivia J S Macleod; Paula MacGregor; R Ellen R Nisbet

doi:10.1016/j.tcsw.2022.100078

In silico identification of Theileria parva surface proteins

Cell Surf. 2022 May 21:8:100078. doi: 10.1016/j.tcsw.2022.100078. eCollection 2022 Dec.

Authors

Nitisha Gurav¹, Olivia J S Macleod², Paula MacGregor³, R Ellen R Nisbet¹

Affiliations

¹ School of Biosciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK.
² Department of Biochemistry, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QW, UK.
³ School of Biological Sciences, University of Bristol, Bristol Life Sciences Building, 24 Tyndall Ave, Bristol BS8 1TQ, UK.

Abstract

East Coast Fever is a devastating African cattle disease caused by the apicomplexan parasite, Theileria parva. Little is known about the cell surface, and few proteins have been identified. Here, we take an in silico approach to identify novel cell surface proteins, and predict the structure of four key proteins.

Keywords: Apicomplexa; East Coast Fever; Parasitology; Theileria.