Seq-ing the mechanisms of migraine

Haley C Cropper; Amynah A Pradhan

doi:10.1016/j.neuron.2022.04.028

Seq-ing the mechanisms of migraine

Neuron. 2022 Jun 1;110(11):1745-1746. doi: 10.1016/j.neuron.2022.04.028.

Authors

Haley C Cropper¹, Amynah A Pradhan²

Affiliations

¹ Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
² Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA. Electronic address: [email protected].

PMID: 35654020
DOI: 10.1016/j.neuron.2022.04.028

Abstract

The trigeminal ganglia (TG) play a crucial role in migraine pathophysiology. In this issue of Neuron, Yang et al. developed a single-cell atlas profiling the transcriptome and epigenome of mouse and human TG, thus providing a roadmap for therapeutic targeting.

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MeSH terms

Humans
Migraine Disorders* / genetics
Neurons
Transcriptome
Trigeminal Ganglion*