Phytochemical index and hypertension in Korean adults using data from the Korea National Health and Nutrition Examination Survey in 2008-2019

Eur J Clin Nutr. 2022 Nov;76(11):1594-1599. doi: 10.1038/s41430-022-01155-w. Epub 2022 Jun 14.

Abstract

Background/objectives: Although previous in vivo and in vitro studies have reported the beneficial effects of phytochemical-rich food on cardiovascular health, limited information is available regarding its' health effect on the community-dwelling population. This is especially true in Korea. Here, we examined the cross-sectional association between phytochemical levels and hypertension in Korean adults.

Subjects/methods: We analyzed data from 38,198 Koreans aged ≥30 years who participated in the Korea National Health and Nutrition Examination Survey (2008-2019) and met the study's inclusion criteria. The Korean version of the Phytochemical Index (PI) was computed based on 24 h recall data. Hypertension was defined based on the American College of Cardiology/American Heart Association definition in 2017. Multivariate logistic regression analysis was used to examine the association between PI and hypertension.

Results: In the multivariable adjusted model, participants in the highest PI quintile had a significantly low prevalence of hypertension (Odd ratio, 0.86; 95% confidence interval, 0.79-0.95). A dose-response analysis confirmed the inverse linearity between PI and hypertension (p for nonlinearity = 0.2634).

Conclusions: Consumption of phytochemical-rich foods may lower the prevalence of hypertension. A large-scale, prospective cohort study is required to validate these findings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Diet*
  • Humans
  • Hypertension* / epidemiology
  • Nutrition Surveys
  • Phytochemicals
  • Prospective Studies
  • Republic of Korea / epidemiology

Substances

  • Phytochemicals