Gamma Secretase Inhibition for a Child With Metastatic Glomus Tumor and Activated NOTCH1
JCO Precis Oncol
.
2022 Jun:6:e2200099.
doi: 10.1200/PO.22.00099.
Authors
Ellen Zhang
1
,
Amber Miller
2
,
Catherine Clinton
2
,
Kylene DeSmith
2
,
Stephan D Voss
3
,
Jon C Aster
4
,
Alanna J Church
5
,
Reza Rahbar
6
,
Nadezhda Eberhart
7
,
Katherine A Janeway
2
,
Steven G DuBois
2
Affiliations
1
Harvard Medical School, Boston, MA.
2
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA.
3
Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA.
4
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
5
Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA.
6
Department of Otolaryngology, Boston Children's Hospital and Harvard Medical School, Boston, MA.
7
Eli Lilly Inc, Indianapolis, IN.
PMID:
35731997
DOI:
10.1200/PO.22.00099
No abstract available
MeSH terms
Amyloid Precursor Protein Secretases*
Cell Line, Tumor
Child
Glomus Tumor*
Humans
Receptor, Notch1 / genetics
Substances
NOTCH1 protein, human
Receptor, Notch1
Amyloid Precursor Protein Secretases