Growth delay: an alternative measure of population health based on child height distributions

Ann Hum Biol. 2022 Mar;49(2):100-108. doi: 10.1080/03014460.2022.2091794. Epub 2022 Jul 18.

Abstract

Background: Indicators of child height, such as mean height-for-age Z-scores (HAZ), height-for-age difference (HAD) and stunting prevalence, do not account for differences in population-average bone developmental stage.

Aim: Propose a measure of child height that conveys the dependency of linear growth on stage rather than chronological age.

Subjects and methods: Using Demographic and Health Surveys (2000-2018; 64 countries), we generated: (1) predicted HAZ at specific ages (HAZ regressed on age); (2) height-age (age at which mean height matches the WHO Growth Standards median); (3) Growth delay (GD), the difference between chronological age and height-age; (4) HAD; and (5) stunting prevalence. Metrics were compared based on secular trends within countries and age-related trajectories within surveys.

Results: In the most recent surveys (N = 64), GDs ranged from 1.9 to 19.1 months at 60 months chronological age. Cross-sectionally, HAZ, HAD and GD were perfectly correlated, and showed similar secular trends. However, age-related trajectories differed across metrics. Accumulating GD with age demonstrated growth faltering as slower than expected growth for children of the same height-age. Resumption of growth at the median for height-age was rarely observed.

Conclusion: GD is a population-level measure of child health that reflects the role of delayed skeletal development in linear growth faltering.

Keywords: Stunting; growth faltering; height-age.

MeSH terms

  • Body Height*
  • Child
  • Family
  • Growth Disorders / epidemiology
  • Humans
  • Infant
  • Population Health*
  • Surveys and Questionnaires