Progress in the Self-Regulation System in Legume Nodule Development-AON (Autoregulation of Nodulation)

Int J Mol Sci. 2022 Jun 15;23(12):6676. doi: 10.3390/ijms23126676.

Abstract

The formation and development of legumes nodules requires a lot of energy. Legumes must strictly control the number and activity of nodules to ensure efficient energy distribution. The AON system can limit the number of rhizobia infections and nodule numbers through the systemic signal pathway network that the aboveground and belowground parts participate in together. It can also promote the formation of nodules when plants are deficient in nitrogen. The currently known AON pathway includes four parts: soil NO3- signal and Rhizobium signal recognition and transmission, CLE-SUNN is the negative regulation pathway, CEP-CRA2 is the positive regulation pathway and the miR2111/TML module regulates nodule formation and development. In order to ensure the biological function of this important approach, plants use a variety of plant hormones, polypeptides, receptor kinases, transcription factors and miRNAs for signal transmission and transcriptional regulation. This review summarizes and discusses the research progress of the AON pathway in Legume nodule development.

Keywords: AON; legumes; nitrogen nutrient; nodule development; phytohormones.

Publication types

  • Review

MeSH terms

  • Fabaceae* / genetics
  • Fabaceae* / metabolism
  • Gene Expression Regulation, Plant
  • Homeostasis
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plant Root Nodulation / genetics
  • Rhizobium* / metabolism
  • Root Nodules, Plant / metabolism
  • Self-Control*
  • Symbiosis / physiology

Substances

  • Plant Proteins

Grants and funding

This study was supported by the foundation of the Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations (lzujbky-2019-kb05; lzujbky-2021-kb05).