DICER1-Associated Anaplastic Sarcoma of the Kidney With Coexisting Activating PDGFRA D842V Mutations and Response to Targeted Kinase Inhibitors in One Patient

JCO Precis Oncol. 2022 Jul:6:e2100554. doi: 10.1200/PO.21.00554.

Authors

Cristina R Antonescu¹, Victor E Reuter¹, Mary Lou Keohan², Sinchun Hwang³, Ping Chi^{2

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Affiliations

¹ Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
² Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
³ Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
⁴ Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY.
⁵ Department of Medicine, Weill Cornell Medical College, New York, NY.

No abstract available

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

DEAD-box RNA Helicases / genetics
Gastrointestinal Stromal Tumors* / genetics
Humans
Kidney
Mutation
Receptor, Platelet-Derived Growth Factor alpha / genetics
Ribonuclease III / genetics
Sarcoma*

Substances

Receptor, Platelet-Derived Growth Factor alpha
DICER1 protein, human
Ribonuclease III
DEAD-box RNA Helicases

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