Radiation therapy-induced left vocal cord paralysis following lung stereotactic body radiation therapy: A case report and review of the literature

Cancer Radiother. 2023 Feb;27(1):69-74. doi: 10.1016/j.canrad.2022.05.004. Epub 2022 Jul 22.

Abstract

We report the case of a 50-year old women with an oncological history of metastatic breast carcinoma who underwent lung stereotactic body radiation therapy (SBRT) of 60Gy in 8 fractions for a left upper lobe metastatic lesion. Seven months later, she complains about hoarseness and weakness of voice. Tumoral relapse and other frequent etiologies were excluded. The diagnosis of radiation induced left recurrent laryngeal nerve paralysis causing left vocal cord paralysis (VCP) was made. The symptomatology did not improve till the disease progression and death of the patient 29 months after SBRT. VCP after lung SBRT is a rare adverse event that has not yet been well described in the medical literature.

Keywords: Lung SBRT; Neuropathie du nerf laryngé récurrent; Paralysie des cordes vocales; Recurrent laryngeal nerve neuropathy; SBRT pulmonaire; Vocal cord paralysis.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Female
  • Hoarseness / complications
  • Hoarseness / diagnosis
  • Humans
  • Lung
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Radiosurgery* / adverse effects
  • Vocal Cord Paralysis* / diagnosis
  • Vocal Cord Paralysis* / etiology