Cancer treatment-related cardiac dysfunction

BMJ Support Palliat Care. 2022 Jul 26:spcare-2022-003832. doi: 10.1136/spcare-2022-003832. Online ahead of print.

Abstract

Objectives: This paper describes cardiotoxicity and cancer treatment-related cardiac dysfunction (CTRCD). Long-term sequelae of treatment are important, and changing, and may manifest when a patient is under the care of a supportive care service.

Methods: Key messages for supportive and palliative care clinicians are outlined to facilitate identification and management of CTRCD.

Results: Not all cardiotoxicity is alike. Types of cardiotoxicity, cardiac complications of immunotherapy, the challenge of autonomic nervous system dysfunction in cancer and management of cardiotoxicity are highlighted.

Conclusions: The key strategies are early detection of cardiotoxicity, monitoring for development of CTRCD during treatment and surveillance in survivorship.

Keywords: cancer; clinical decisions; heart failure.