Clinical improvement of a toddler with COVID-19 focal cerebral arteriopathy possibly due to intra-arterial nimodipine

Eur J Paediatr Neurol. 2022 Sep:40:40-43. doi: 10.1016/j.ejpn.2022.07.007. Epub 2022 Jul 31.

Abstract

Pediatric stroke is considered an infrequent complication of COVID-19. Focal cerebral arteriopathy (FCA) is one of the most common causes of arterial ischemic stroke in a previously healthy child. The present report describes a toddler with FCA most likely induced by SARS-CoV-2 infection who showed significant clinical improvement that may be related to injection of intra-arterial nimodipine. To our knowledge, this is the first reported use of nimodipine in this setting.

MeSH terms

  • COVID-19* / complications
  • Cerebral Arterial Diseases* / complications
  • Cerebral Arterial Diseases* / diagnostic imaging
  • Cerebral Arterial Diseases* / drug therapy
  • Child
  • Child, Preschool
  • Humans
  • Nimodipine / therapeutic use
  • SARS-CoV-2
  • Stroke* / diagnostic imaging
  • Stroke* / drug therapy
  • Stroke* / etiology

Substances

  • Nimodipine