Coats disease in female population: A comparison of clinical presentation and outcomes

Front Med (Lausanne). 2022 Aug 4:9:879110. doi: 10.3389/fmed.2022.879110. eCollection 2022.

Abstract

Purpose: To compare clinical characteristics at presentation and outcomes of Coats disease between females and males.

Methods: In this retrospective, consecutive case series we included all children diagnosed with Coats disease in a single tertiary referral center. Initial clinical presentation, treatment and outcomes were collected.

Results: A total of 158 children were included, of whom 29 (18.3%) were females and 11 (6.9%) had bilateral involvement. Age at diagnosis and disease stage were similar between females and males. Females had more bilateral involvement (p < 0.001) and tended to have a worse visual acuity at diagnosis (p = 0.05). At last follow-up, visual acuity and anatomical outcome after treatment were similar between genders.

Conclusion: Female patients with Coats disease had more bilateral involvement and tended to have worse visual acuity at presentation. Clinical presentation and outcomes seemed to be similar between genders.

Keywords: Coats disease; bilateral disease; female population; pediatric retinal detachment; pediatric retinal disease.