Diabetic Patients with COVID-19 Complications: Insights into Prevalence, Prognosis, Combination Medications, and Underlying Mechanisms

Background: COVID-19 may have an impact on diabetes pathogenesis. For people with COVID-19 infection as well as for healthy individuals, blood glucose control is essential. Nowadays, innovations like telemedicine are helpful in treating diabetic patients.

Objectives: We examined the data on the link between diabetes and COVID-19, the pathogenesis of diabetes, and treatment of COVID-19 infection in diabetic patients.

Methods: Up until October 2, 2021, the key terms 'COVID-19,' 'SARSCoV2,' 'diabetes,' and 'antidiabetic therapy' were searched in the PubMed database and Google Scholar. The full texts of the articles were accessed.

Results: Some diseases, for instance, diabetes, are continuously suggested as risk factor which result in the severity and mortality of COVID-19. However, to date, there are no comprehensive studies aiming to explain the exact relationship between diabetes and COVID-19. COVID-19 has been linked to an increased incidence and severity in diabetic patients. COVID-19 may have an impact on diabetes pathogenesis. Blood glucose control is critical not only for COVID-19-infected patients but also for those who do not have the condition. In today's world, innovations like telemedicine are helpful in treating diabetic patients.

Conclusion: Thus, this study aims to summarize the evidence about diabetes and COVID-19 outbreak through a systematic review and meta-analysis approach. COVID-19 has been linked to an increased incidence and severity in diabetic patients.