Hepatorenal Syndrome: From the Beginning to Now

Latanja L Divens; Sherry L Rivera

doi:10.1016/j.cnc.2022.04.010

Hepatorenal Syndrome: From the Beginning to Now

Crit Care Nurs Clin North Am. 2022 Sep;34(3):321-329. doi: 10.1016/j.cnc.2022.04.010.

Authors

Latanja L Divens¹, Sherry L Rivera²

Affiliations

¹ Louisiana State University Health New Orleans, School of Nursing, 1900 Gravier Street, New Orleans, LA 70112, USA.
² Louisiana State University Health New Orleans, School of Nursing, 1900 Gravier Street, New Orleans, LA 70112, USA. Electronic address: [email protected].

PMID: 36049851
DOI: 10.1016/j.cnc.2022.04.010

Abstract

Cirrhosis is a complex disease and has devastating effects on the liver. People living with the condition are at risk for many complications such as hepatorenal syndrome (HRS). If diagnosed with this condition, the prognosis is often poor. Therefore, it is imperative that treating providers are aware of the symptoms and methods to either prevent or adequately treat the syndrome. Timely referral, prevention, early recognition, and initiation of treatment are key components for prevention or improving the prognosis for HRS. Excluding potentially contributing factors and/or conditions is also vitally important for diagnostic purposes. Comorbid conditions may be present and further complicate diagnosis. Fluid volume replacement, administration of albumin, and vasoconstrictors as warranted are important for improving the hemodynamic status and potential reversal of HRS-acute kidney injury (HRS-AKI).

Keywords: Acute kidney injury; Cirrhosis; Hepatorenal syndrome.

Publication types

Review

MeSH terms

Acute Kidney Injury* / diagnosis
Acute Kidney Injury* / etiology
Acute Kidney Injury* / therapy
Hepatorenal Syndrome* / diagnosis
Hepatorenal Syndrome* / etiology
Hepatorenal Syndrome* / therapy
Humans
Liver Cirrhosis / complications
Liver Transplantation* / adverse effects
Vasoconstrictor Agents

Substances

Vasoconstrictor Agents