T_FH cells regulate antibody affinity and determine the outcomes of anaphylaxis

J Allergy Clin Immunol. 2022 Nov;150(5):1042-1044. doi: 10.1016/j.jaci.2022.08.018. Epub 2022 Sep 3.

Authors

Jyoti K Lama¹, Hirohito Kita²

Affiliations

¹ Department of Immunology, Mayo Clinic Rochester and Mayo Clinic Arizona, Scottsdale, Ariz; Immunology Program, Mayo Graduate School of Biomedical Sciences, Rochester and Scottsdale, Ariz.
² Department of Immunology, Mayo Clinic Rochester and Mayo Clinic Arizona, Scottsdale, Ariz; Division of Allergy, Asthma and Clinical Immunology and Department of Medicine, Mayo Clinic Arizona, Scottsdale, Ariz. Electronic address: [email protected].

No abstract available

Keywords: IgE; IgG; T(FH) cells; affinity; anaphylaxis; glycosylation.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

Anaphylaxis*
Antibody Affinity
Humans
Immunoglobulin E
Immunoglobulin G

Substances

Immunoglobulin E
Immunoglobulin G

Grants and funding

R37 AI071106/AI/NIAID NIH HHS/United States