Comparison of the Risk of Recurrent Clostridioides Difficile Infections Among Patients in 2018 Versus 2013

Open Forum Infect Dis. 2022 Aug 17;9(9):ofac422. doi: 10.1093/ofid/ofac422. eCollection 2022 Sep.

Abstract

Among persons with an initial Clostridioides difficile infection (CDI) across 10 US sites in 2018 compared with 2013, 18.3% versus 21.1% had ≥1 recurrent CDI (rCDI) within 180 days. We observed a 16% lower adjusted risk of rCDI in 2018 versus 2013 (P < .0001).

Keywords: Clostridioides difficile; infection; recurrent.