Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation

Harry J Iland; Nigel Russell; Richard Dillon; Andre C Schuh; Aditya Tedjaseputra; Andrew Wei; Asim Khwaja; Steven Knapper; Steven W Lane; John Reynolds; Mary Frances McMullin; Annalise Martin; Peter Tan; David C Taussig; Anny Wong; John Taper; Christina Fraga; Richard Kelly; Kiran Tawana; Priyanka Mehta; Alain Mina; Jessica K Altman; Ingolf Mølle; Sudhir Tauro; Eleni Tholouli

doi:10.1182/bloodadvances.2022007126

Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation

Blood Adv. 2023 Jun 13;7(11):2580-2585. doi: 10.1182/bloodadvances.2022007126.

Authors

Harry J Iland¹, Nigel Russell², Richard Dillon³, Andre C Schuh⁴, Aditya Tedjaseputra⁵, Andrew Wei⁵, Asim Khwaja⁶, Steven Knapper⁷, Steven W Lane⁸, John Reynolds⁹, Mary Frances McMullin¹⁰, Annalise Martin¹¹, Peter Tan¹¹, David C Taussig¹², Anny Wong¹³, John Taper¹⁴, Christina Fraga¹⁵, Richard Kelly¹⁶, Kiran Tawana¹⁷, Priyanka Mehta¹⁸, Alain Mina¹⁹, Jessica K Altman²⁰, Ingolf Mølle²¹, Sudhir Tauro²², Eleni Tholouli²³

Affiliations

¹ Institute of Haematology, Royal Prince Alfred Hospital and University of Sydney, Camperdown, Australia.
² Department of Haematology, Guy's and St Thomas' Hospital, London, United Kingdom.
³ Department of Medical and Molecular Genetics, Kings College London, London, United Kingdom.
⁴ Department of Medical Oncology & Hematology, Princess Margaret Cancer Centre, Toronto, Canada.
⁵ Department of Haematology, Alfred Hospital, Melbourne, Australia.
⁶ Department of Haematology, University College Hospital, London, United Kingdom.
⁷ Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
⁸ Cancer Care Services, Royal Brisbane & Women's Hospital and University of Queensland, Brisbane, Australia.
⁹ Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.
¹⁰ School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
¹¹ Haematology Department, Royal Perth Hospital, Perth, Australia.
¹² Royal Marsden Hospital, London, United Kingdom.
¹³ Department of Paediatric Oncology and Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
¹⁴ Department of Haematology, Nepean Hospital, Nepean, Australia.
¹⁵ Division of Hematology, Department of Medicine, Dalhousie University, Halifax, Canada.
¹⁶ Department of Haematology, St James's University Hospital, Leeds, United Kingdom.
¹⁷ Department of Haematology, Addenbrookes Hospital, Cambridge, United Kingdom.
¹⁸ Bristol Haematology and Oncology Centre, University Hospitals of Bristol and Weston NHS Trusts, Bristol, United Kingdom.
¹⁹ Division of Bone Marrow Transplant and Cellular Therapies, Department of Medicine, Stanford University, Stanford, CA.
²⁰ Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
²¹ Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.
²² Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, Dundee, United Kingdom.
²³ Department of Adult Haematology, Manchester Royal Infirmary, Manchester, United Kingdom.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Leukemia, Promyelocytic, Acute* / diagnosis
Leukocyte Count
Leukocytosis

Grants and funding

DH_/Department of Health/United Kingdom