Maternal Anti-Ro/SSA Autoantibodies and Prolonged PR Interval in a Competitive Athlete: Beyond Training-Induced Electrical Remodeling

Chiara Fusi; Pietro Enea Lazzerini; Luna Cavigli; Marta Focardi; Maurizio Acampa; Matteo Cameli; Serafina Valente; Flavio D'Ascenzi

doi:10.1016/j.jaccas.2022.05.032

Maternal Anti-Ro/SSA Autoantibodies and Prolonged PR Interval in a Competitive Athlete: Beyond Training-Induced Electrical Remodeling

JACC Case Rep. 2022 Sep 7;4(17):1098-1103. doi: 10.1016/j.jaccas.2022.05.032.

Authors

Chiara Fusi¹, Pietro Enea Lazzerini², Luna Cavigli¹, Marta Focardi¹, Maurizio Acampa³, Matteo Cameli¹, Serafina Valente¹, Flavio D'Ascenzi¹

Affiliations

¹ Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
² Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy.
³ Stroke Unit, University Hospital of Siena, Italy.

Abstract

Prolongation of the PR interval is common among competitive athletes. However, further investigations should be performed when the PR interval is markedly prolonged. We report the case of a young male athlete with an autoimmune-mediated atrioventricular block due to circulating anti-Ro/SSA-antibodies in the mother (late progressive congenital form). (Level of Difficulty: Advanced.).

Keywords: AV, atrioventricular; ECG, electrocardiogram; anti-Ro/SSA, anti-Sjögren-syndrome-related antigen A antibodies; autoimmune; bradycardia; electrocardiogram; exercise; immunization.

Publication types

Case Reports