Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML
Blood Adv
.
2023 Mar 28;7(6):1040-1044.
doi: 10.1182/bloodadvances.2022007988.
Authors
Aarif M N Batcha
1
2
,
Nele Buckup
3
,
Stefanos A Bamopoulos
3
4
,
Vindi Jurinovic
1
3
,
Maja Rothenberg-Thurley
3
,
Hanna Gittinger
3
,
Bianka Ksienzyk
3
,
Annika Dufour
3
,
Stephanie Schneider
3
5
,
Mika Kontro
6
7
8
,
Joseph Saad
7
,
Caroline A Heckmann
7
,
Cristina Sauerland
9
,
Dennis Görlich
9
,
Wolfgang E Berdel
10
,
Bernhard J Wörmann
11
,
Utz Krug
12
,
Jan Braess
13
,
Ulrich Mansmann
1
2
14
15
,
Wolfgang Hiddemann
3
14
15
,
Karsten Spiekermann
3
14
15
,
Klaus H Metzeler
16
,
Tobias Herold
3
14
15
Affiliations
1
Institute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany.
2
Data Integration for Future Medicine (DIFUTURE), LMU Munich, Munich, Germany.
3
Department of Medicine III, Laboratory for Leukemia Diagnostics, University Hospital, LMU Munich, Munich, Germany.
4
Department of Hematology, Oncology and Tumor Immunology (Campus Benjamin Franklin), Charité University Medicine Berlin, Berlin, Germany.
5
Institute of Human Genetics, University Hospital, LMU Munich, Munich, Germany.
6
Department of Haematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
7
Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
8
Foundation for the Finnish Cancer Institute, Helsinki, Finland.
9
Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
10
Department of Medicine A, Hematology and Oncology, University of Münster, Münster, Germany.
11
German Society of Hematology and Oncology, Berlin, Germany.
12
Department of Medicine III, Hospital Leverkusen, Leverkusen, Germany.
13
Department of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany.
14
German Cancer Consortium, Heidelberg, Germany.
15
German Cancer Research Center, Heidelberg, Germany.
16
Department of Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.
PMID:
36149944
PMCID:
PMC10036512
DOI:
10.1182/bloodadvances.2022007988
No abstract available
Publication types
Research Support, Non-U.S. Gov't
MeSH terms
Biomarkers, Tumor
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Polymorphism, Single Nucleotide*
Prognosis
Substances
Biomarkers, Tumor