Consensus statement on the definition of orthostatic hypertension endorsed by the American Autonomic Society and the Japanese Society of Hypertension

Clin Auton Res. 2023 Feb;33(1):69-73. doi: 10.1007/s10286-022-00897-8. Epub 2022 Sep 29.

Abstract

We propose a consensus definition of "an exaggerated orthostatic pressor response" in subjects in whom systolic blood pressure increases ≥ 20 mmHg when going from supine to standing posture. This definition can be extended for seated to standing measurements. We reserve the term "orthostatic hypertension" for when this pressor response leads to an upright systolic blood pressure ≥ 140 mmHg. We believe this consensus definition will help in the study of the pathophysiology, clinical impact, and potential treatment of these entities, and identification of patients who are at greater cardiovascular risk.

Keywords: Adrenergic; Autonomic nervous system; Baroreflex; Circadian rhythm; Orthostatic hypertension; Orthostatic pressor response; Sympathetic nervous system.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autonomic Nervous System
  • Blood Pressure
  • Humans
  • Hypertension*
  • Hypotension, Orthostatic* / drug therapy
  • Japan
  • Posture / physiology
  • United States