Paediatric epilepsy surgery: Techniques and outcomes

J Paediatr Child Health. 2022 Nov;58(11):1952-1957. doi: 10.1111/jpc.16236. Epub 2022 Oct 5.

Abstract

Epilepsy is a neurological condition characterised by recurrent and persistent seizures. For paediatric patients, achieving early seizure freedom can have positive impacts on cognition, development, social integration and mental health, leading to improved quality of life. In general, one third of patients with epilepsy are refractory to medication; for these patients, epilepsy surgery may offer the only chance for improved seizure control. Epilepsy surgery as a therapeutic intervention has become increasingly accepted in the past few decades, with more diverse options available (including neuromodulatory and minimally invasive techniques). In this context, we discuss here the pre-operative workup for paediatric patients with medically refractory epilepsy and provide an updated review on current and emerging surgical therapies for this condition. We also discuss the clinical, neuropsychological, quality of life and economic impacts of epilepsy surgery.

Keywords: epilepsy; neurosurgery; operative technique; outcomes; paediatric.

Publication types

  • Review

MeSH terms

  • Child
  • Cognition
  • Drug Resistant Epilepsy* / surgery
  • Electroencephalography
  • Epilepsy* / drug therapy
  • Epilepsy* / surgery
  • Humans
  • Quality of Life
  • Seizures
  • Treatment Outcome