Glycosylation and the global virome

Cassandra L Pegg; Benjamin L Schulz; Benjamin A Neely; Gregory F Albery; Colin J Carlson

doi:10.1111/mec.16731

Glycosylation and the global virome

Mol Ecol. 2023 Jan;32(1):37-44. doi: 10.1111/mec.16731. Epub 2022 Oct 21.

Authors

Cassandra L Pegg¹, Benjamin L Schulz¹, Benjamin A Neely², Gregory F Albery³, Colin J Carlson^{3

4

5}

Affiliations

¹ School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia.
² National Institute of Standards and Technology, Charleston, South Carolina, USA.
³ Department of Biology, Georgetown University, Washington, District of Columbia, USA.
⁴ Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, District of Columbia, USA.
⁵ Center for Global Health Science and Security, Georgetown University Medical Center, Washington, District of Columbia, USA.

Abstract

The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation - and harnessing it for predictive science - could help close the molecular gap in zoonotic risk assessment.

Keywords: Microbial Biology; Modelling; Molecular Evolution; Viral Ecology; Viral Evolution; glycosylation.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Glycosylation
Virome*
Viruses* / genetics