Help from commensals: β-hex to regulate gut immunity

Marie-Laure Michel

doi:10.1016/j.chom.2022.09.007

Help from commensals: β-hex to regulate gut immunity

Cell Host Microbe. 2022 Oct 12;30(10):1349-1351. doi: 10.1016/j.chom.2022.09.007.

Author

Marie-Laure Michel¹

Affiliation

¹ Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France; Paris Center for Microbiome Medicine (PaCeMM), Fédération Hospitalo-Universitaire, Paris, France. Electronic address: [email protected].

PMID: 36228583
DOI: 10.1016/j.chom.2022.09.007

Abstract

In a recent Science issue, Bousbaine et al. (2022) identified β-N-acetylhexosaminidase, a conserved antigen expressed by commensals that drives expansion and differentiation of intestinal intra-epithelial cells and protects against gut inflammation.

MeSH terms

Intestines
Symbiosis*
beta-N-Acetylhexosaminidases*

Substances

beta-N-Acetylhexosaminidases