The leading school of thought views fibromyalgia as a central sensitization syndrome. Nociplastic pain is the recently proposed term to mechanistically explain central sensitization. Accumulating research suggests an alternate explanation; fibromyalgia can be conceptualized as a neuropathic pain syndrome and dorsal root ganglia (not the brain) as the primary fibromyalgia pain source. There is no need to propose nociplastic pain as new chronic pain mechanism.
Keywords: Central sensitization syndrome; Dorsal root ganglia; Dysautonomia; Fibromyalgia; Neuropathic pain; Nociplastic pain.
© 2022. The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR).