Brain death due to neuroaspergillosis in a patient with COVID-19

Rev Esp Anestesiol Reanim (Engl Ed). 2022 Nov;69(9):592-596. doi: 10.1016/j.redare.2022.01.004. Epub 2022 Sep 30.

Abstract

Co-infections between SARS-CoV-2 and other pathogens is an important consideration for the treatment of patients with COVID-19. Aspergillus infections are part of this consideration since they present high morbidity and mortality. We present the case of a patient with COVID-19 and Aspergillus Fumigatus coinfection that evolves with brain death due to multiple heterogeneous lesions in the brain, which after a post-mortem biopsy found pathological lesions compatible with Aspergillus.

Las coinfecciones entre SARS-CoV-2 y otros patógenos son una cuestión importante para el tratamiento de los pacientes con COVID-19. Las infecciones por Aspergillus forman parte de esta consideración, ya que presentan elevada morbilidad y mortalidad. Presentamos el caso de un paciente con coinfección de COVID-19 y Aspergillus fumigatus que evolucionó a muerte cerebral debido a múltiples lesiones heterogéneas en el cerebro donde, tras biopsia post-mortem, se encontraron lesiones patológicas compatibles con Aspergillus.

Keywords: Brain death; Muerte cerebral; Neuroaspergillosis; Neuroaspergilosis.

Publication types

  • Case Reports

MeSH terms

  • Aspergillus fumigatus
  • Brain Death
  • COVID-19* / complications
  • Humans
  • Neuroaspergillosis* / pathology
  • Neuroaspergillosis* / therapy
  • SARS-CoV-2