Scrotal fibrous hamartoma of infancy: A case report and literature review of a rare tumor of the genitourinary tract

Savannah Starr; Neil Mendhiratta; Paul J Iskander; Huihui Ye; Renea Sturm

doi:10.1016/j.eucr.2022.102218

Scrotal fibrous hamartoma of infancy: A case report and literature review of a rare tumor of the genitourinary tract

Urol Case Rep. 2022 Sep 12:45:102218. doi: 10.1016/j.eucr.2022.102218. eCollection 2022 Nov.

Authors

Savannah Starr¹, Neil Mendhiratta¹, Paul J Iskander², Huihui Ye³, Renea Sturm¹

Affiliations

¹ Department of Urology, University of California Los Angeles, USA.
² Department of Radiology, University of California Los Angeles, USA.
³ Department of Pathology, University of California Los Angeles, USA.

Abstract

Fibrous hamartoma of infancy (FHI) is a rare, benign soft tissue lesion observed in infants characterized histologically by triphasic appearance of bland fibroblastic fascicles, mature adipose tissue, and nodules of primitive myxoid mesenchyme. Preoperative and intraoperative recognition of FHI presents a significant diagnostic challenge due to nonspecific imaging findings and its histologic similarities to alternate benign and malignant entities. Management requires complete local excision and clinical follow-up to monitor for recurrence. Here, we present the diagnosis, management, and two-year follow-up of a 13-month-old boy with a scrotal FHI in addition to a comprehensive literature review of this entity.

Keywords: Fibrous hamartoma of infancy; Genitourinary tract; Paratesticular tumors; Pediatric testicular tumors.

Publication types

Case Reports