Pharmacological thiamine levels as a therapeutic approach in Alzheimer's disease

Front Med (Lausanne). 2022 Oct 4:9:1033272. doi: 10.3389/fmed.2022.1033272. eCollection 2022.

¹ Weill Cornell Medicine, Brain and Mind Research Institute, Burke Neurological Institute, White Plains, NY, United States.
² Alzheimer's Disease Cooperative Study and Department of Neurosciences, University of California, San Diego, San Diego, CA, United States.
³ Proteomics and Metabolomics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY, United States.
⁴ Department of Neuroscience, Georgetown University, Washington, DC, United States.
⁵ Departments of Medicine and Epidemiology, Columbia University Irving Medical Center, New York, NY, United States.

Abstract

of the study.

Keywords: Advanced Glycation Endproducts (AGE); Alzheimer's disease; benfotiamine; cognition; glucose metabolism; therapy; thiamine.