During 2013-2021, increased prevalence of oxacillinase 232-producing Enterobacterales was observed in France, mostly driven by its emergence in Klebsiella pneumoniae. Whole-genome sequencing identified that oxacillinase 232-producing K. pneumoniae belonged to 14 sequence types (STs), among which 2 polyclonal high-risk clones, ST-231 and ST-2096, were overrepresented.
Keywords: Enterobacterales; France; Klebsiella pneumoniae; OXA-232; antimicrobial resistance; carbapenemase; epidemiology; oxacillin.