Loss of IDH mutation or secondary tumour manifestation? Evolution of an IDH-mutant and 1p/19q-codeleted oligodendroglioma after 15 years of continuous temozolomide treatment and radiotherapy: A case report

Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12859. doi: 10.1111/nan.12859. Epub 2022 Dec 14.
No abstract available

Keywords: DNA methylation; case report; dual genotype; isocitrate dehydrogenase; molecular pathology; oligodendroglioma; secondary gliomagenesis; temozolomide.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms* / pathology
  • Chromosomes, Human, Pair 1
  • Chromosomes, Human, Pair 19
  • Glioma* / pathology
  • Humans
  • Isocitrate Dehydrogenase / genetics
  • Mutation
  • Oligodendroglioma* / pathology
  • Temozolomide

Substances

  • Temozolomide
  • Isocitrate Dehydrogenase