Richter transformation to aggressive plasmablastic neoplasm related to selection of a BTK-mutated clone in a patient with CLL/SLL treated by ibrutinib

Leuk Lymphoma. 2023 Jan;64(1):242-245. doi: 10.1080/10428194.2022.2140286. Epub 2022 Nov 6.

Authors

Barina Aqil¹, Amandeep Kaur¹, Josean Ramos¹, Madina Sukhanova¹, Shuo Ma², Juehua Gao¹, Xinyan Lu¹, Yi-Hua Chen¹, Qing Chen¹

Affiliations

¹ Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
² Robert H. Lurie Comprehensive Cancer Center, Division of Hematology-Oncology, Department of Medicine, Feinberg School of Medicine, Chicago, IL, USA.

PMID: 36336991
DOI: 10.1080/10428194.2022.2140286

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adenine
Humans
Leukemia, Lymphocytic, Chronic, B-Cell* / diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell* / drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell* / genetics
Piperidines
Plasma Cells

Substances

Adenine
ibrutinib
Piperidines