Neuroimaging in Pediatric Stroke

Bin Jiang; Mark T Mackay; Nicholas Stence; Trish Domi; Nomazulu Dlamini; Warren Lo; Max Wintermark

doi:10.1016/j.spen.2022.100989

Neuroimaging in Pediatric Stroke

Semin Pediatr Neurol. 2022 Oct:43:100989. doi: 10.1016/j.spen.2022.100989. Epub 2022 Aug 28.

Authors

Bin Jiang¹, Mark T Mackay², Nicholas Stence³, Trish Domi⁴, Nomazulu Dlamini⁵, Warren Lo⁶, Max Wintermark⁷

Affiliations

¹ Department of Radiology, Neuroradiology Section, Stanford University, Stanford, CA. Electronic address: [email protected].
² Murdoch Children's Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Victoria, Australia. Electronic address: [email protected].
³ Department of Radiology, pediatric Neuroradiology Section, University of Colorado School of Medicine, Aurora, CO.
⁴ Department of Neurology, Hospital for Sick Children, Toronto, Canada. Electronic address: [email protected].
⁵ Department of Neurology, Hospital for Sick Children, Toronto, Canada. Electronic address: [email protected].
⁶ Department of Pediatrics and Neurology, The Ohio State University & Nationwide Children's Hospital, Columbus, OH. Electronic address: [email protected].
⁷ Department of Neuroradiology, University of Texas MD Anderson Center, Houston, TX. Electronic address: [email protected].

PMID: 36344022
DOI: 10.1016/j.spen.2022.100989

Abstract

Pediatric stroke is unfortunately not a rare condition. It is associated with severe disability and mortality because of the complexity of potential clinical manifestations, and the resulting delay in seeking care and in diagnosis. Neuroimaging plays an important role in the multidisciplinary response for pediatric stroke patients. The rapid development of adult endovascular thrombectomy has created a new momentum in health professionals caring for pediatric stroke patients. Neuroimaging is critical to make decisions of identifying appropriate candidates for thrombectomy. This review article will review current neuroimaging techniques, imaging work-up strategies and special considerations in pediatric stroke. For resources limited areas, recommendation of substitute imaging approaches will be provided. Finally, promising new techniques and hypothesis-driven research protocols will be discussed.

Keywords: CT; DSA; MRI; imaging; pediatric; stroke.

Publication types

Review

MeSH terms

Adult
Child
Humans
Neuroimaging* / methods
Stroke* / diagnostic imaging
Stroke* / etiology
Stroke* / therapy
Thrombectomy / adverse effects
Thrombectomy / methods
Treatment Outcome