Synthetic cathinones and cardiotoxicity risks

Clin Ter. 2022 Nov-Dec;173(6):524-525. doi: 10.7417/CT.2022.2475.

Abstract

Recently, there has been a worldwide rise in the popularity and abuse of synthetic cathinones. The spectrum of side effects caused by the intake of these drugs of abuse is very wide since they act on different systems with various mechanisms of action, they appear to be involved in different cardiac events, including myocardial infarction and sudden cardiac death due to fatal arrhythmias. Overall, khat users have a higher risk of death, recurrent myocardial ischemia, cardiogenic shock, ventricular arrhythmia, and stroke compared with non-khat user.

Keywords: Synthetic cathinones; cardiotoxicity; myocardial dysfunction.

Publication types

  • Letter

MeSH terms

  • Alkaloids* / adverse effects
  • Arrhythmias, Cardiac / chemically induced
  • Cardiotoxicity / etiology
  • Humans
  • Myocardial Infarction*

Substances

  • cathinone
  • Alkaloids