[Drug abuse of pregabalin - state of the situation, risks and means of control]

Ann Pharm Fr. 2023 May;81(3):419-424. doi: 10.1016/j.pharma.2022.11.005. Epub 2022 Nov 12.
[Article in French]

Abstract

Pregabalin is an anticonvulsant widely used for the treatment of epilepsy and neuropathic pain. However, there is a growing concern about its misuse, particularly among drug users and patients with substance use disorders (SUD). It is often used in combination with other psychoactive molecules and at levels well above the recommended doses. Increasing cases of overdose and death associated with the misuse of pregabalin have been reported worldwide. Therefore, raising prescribers' awareness of this scourge is mandatory and the role of the pharmacist is crucial in reducing this phenomenon.

Keywords: Means of control; Moyens de lutte; Pregabalin; Prégabaline; Risks; Risques; Situation; Status; Toxicomania; Toxicomanie.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Anticonvulsants / adverse effects
  • Drug Overdose* / prevention & control
  • Gabapentin / adverse effects
  • Humans
  • Pregabalin / adverse effects
  • Substance-Related Disorders* / prevention & control

Substances

  • Pregabalin
  • Gabapentin
  • Anticonvulsants