PROTAC technology as a novel tool to identify the target of lathyrane diterpenoids

Acta Pharm Sin B. 2022 Nov;12(11):4262-4265. doi: 10.1016/j.apsb.2022.07.007. Epub 2022 Jul 16.

Yanli Wu¹, Yueying Yang¹, Wang Wang¹, Dejuan Sun¹, Jing Liang¹, Man Zhu¹, Hua Li^{1

2

3}, Lixia Chen¹

¹ Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
² College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
³ School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

No abstract available

Keywords: Anti-inflammation; Lathyrane diterpenoids; MAFF; PROTAC; Target identification.