Favourable outcomes of conservatively managed acute abdomen associated with multisystem inflammatory syndrome in children during the COVID-19 pandemic

ANZ J Surg. 2023 Jan;93(1-2):108-114. doi: 10.1111/ans.18162. Epub 2022 Nov 21.

Abstract

Backgrounds: Abdominal pain is one of the most common symptoms of multisystem inflammatory syndrome in children (MIS-C). Abdominal pain can vary from mild to severe and may present as acute abdomen. Severe abdominal pain in patients with MIS-C should be differentiated from surgical causes of acute abdomen to prevent unnecessary surgery.

Methods: The diagnosis of MIS-C was based on WHO and CDC recommended criteria. Records of children treated for MIS-C between September 2020 and January 2021 were reviewed retrospectively.

Results: In a short time, we encountered seven patients who were diagnosed with MIS-C and showed acute abdomen findings. There were four male and three female patients. The median age was 9 years. Fever, abdominal pain and distension were present in all. The median duration of symptoms was 4 days. Five patients had general abdominal tenderness mimicking acute abdomen. Three patients had right lower quadrant tenderness mimicking acute appendicitis. After the initiation of immunomodulatory therapy and antibiotics, the physical examination findings were improved step by step in all. The median time to initiate oral feeding was 2 days. The median length of hospitalization time was 8 days.

Conclusion: Serial abdominal examinations performed by the same surgeon enabled us to follow these patients conservatively and thus avoid unnecessary surgical intervention.

Keywords: COVID-19; MIS-C; abdominal pain; children.

MeSH terms

  • Abdomen, Acute* / diagnosis
  • Abdomen, Acute* / etiology
  • Abdomen, Acute* / therapy
  • Abdominal Pain / diagnosis
  • Abdominal Pain / etiology
  • COVID-19* / complications
  • Child
  • Female
  • Humans
  • Male
  • Pandemics
  • Retrospective Studies
  • Systemic Inflammatory Response Syndrome

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related