Maternal Macro- and Micronutrient Intake During Pregnancy: Does It Affect Allergic Predisposition in Offspring?

Katherine Stumpf; Julie Mirpuri

doi:10.1016/j.iac.2022.07.006

Maternal Macro- and Micronutrient Intake During Pregnancy: Does It Affect Allergic Predisposition in Offspring?

Immunol Allergy Clin North Am. 2023 Feb;43(1):27-42. doi: 10.1016/j.iac.2022.07.006. Epub 2022 Oct 28.

Authors

Katherine Stumpf¹, Julie Mirpuri²

Affiliations

¹ Department of Pediatrics, Division of Neonatal-Perinatal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Boulevard- Suite F3.302, Dallas, TX 75390-9063, USA. Electronic address: [email protected].
² Department of Pediatrics, Division of Neonatal-Perinatal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Boulevard- Suite F3.302, Dallas, TX 75390-9063, USA. Electronic address: [email protected].

PMID: 36411006
DOI: 10.1016/j.iac.2022.07.006

Abstract

This review article explores the available literature on the association of maternal nutrient intake with development of allergies in offspring. It examines the mechanisms for maternal diet-mediated effects on offspring immunity and dissects recent human and animal studies that evaluate the role of both maternal macro- and micronutrient intake on offspring susceptibility to asthma, eczema, food allergy, and atopy.

Keywords: Allergy; Eczema; Maternal diet; Nutrients; Offspring; Vitamins.

Publication types

Review
Research Support, N.I.H., Extramural

MeSH terms

Animals
Asthma*
Diet
Eating
Eczema*
Female
Food Hypersensitivity* / epidemiology
Humans
Pregnancy

Grants and funding

R01 DK121975/DK/NIDDK NIH HHS/United States