Prognostic implications of mono-hit and multi-hit TP53 alterations in patients with acute myeloid leukemia and higher risk myelodysplastic syndromes treated with azacitidine-based therapy

MeSH terms

• Antimetabolites, Antineoplastic
• Azacitidine
• Humans
• Leukemia, Myeloid, Acute* / chemically induced
• Leukemia, Myeloid, Acute* / drug therapy
• Leukemia, Myeloid, Acute* / genetics
• Myelodysplastic Syndromes* / drug therapy
• Myelodysplastic Syndromes* / genetics
• Prognosis
• Tumor Suppressor Protein p53 / genetics