A review of testosterone supplementation and cardiovascular risk

Rom J Intern Med. 2023 Mar 16;61(1):35-40. doi: 10.2478/rjim-2022-0022. Print 2023 Mar 1.

Abstract

Testosterone therapy is commonly utilized to treat hypogonadism. After diagnosis with morning serum testosterone level in patients with symptoms of hypogonadism, therapy has been shown to improve symptoms. Research focusing on cardiovascular risks associated with testosterone therapy has produced contradictory statements. We review trials that have investigated the impact of testosterone supplementation on heart failure, coronary artery disease, and myocardial ischemia.

Keywords: cardiovascular risk; supplementation; testosterone.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / complications
  • Coronary Artery Disease* / complications
  • Dietary Supplements / adverse effects
  • Heart Disease Risk Factors
  • Hormone Replacement Therapy
  • Humans
  • Hypogonadism* / complications
  • Hypogonadism* / drug therapy
  • Risk Factors
  • Testosterone / adverse effects

Substances

  • Testosterone