Cardiovascular, Pulmonary, and Neuropsychiatric Short- and Long-Term Complications of COVID-19

Małgorzata Kobusiak-Prokopowicz; Katarzyna Fułek; Michał Fułek; Konrad Kaaz; Andrzej Mysiak; Donata Kurpas; Jan Aleksander Beszłej; Anna Brzecka; Jerzy Leszek

doi:10.3390/cells11233882

Cardiovascular, Pulmonary, and Neuropsychiatric Short- and Long-Term Complications of COVID-19

Cells. 2022 Dec 1;11(23):3882. doi: 10.3390/cells11233882.

Authors

Małgorzata Kobusiak-Prokopowicz¹, Katarzyna Fułek², Michał Fułek³, Konrad Kaaz¹, Andrzej Mysiak¹, Donata Kurpas⁴, Jan Aleksander Beszłej⁵, Anna Brzecka⁶, Jerzy Leszek⁵

Affiliations

¹ Department of Cardiology, Institute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
² Lower Silesian Oncology, Pulmonology and Hematology Center, 53-413 Wroclaw, Poland.
³ Department and Clinic of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
⁴ Department and Clinic of Family Medicine, Wroclaw Medical University, 51-141 Wroclaw, Poland.
⁵ Department and Clinic of Psychiatry, Wroclaw Medical University, 50-367 Wroclaw, Poland.
⁶ Department of Pulmonology and Lung Oncology, Wroclaw Medical University, 53-439 Wroclaw, Poland.

Abstract

Beginning with the various strategies of the SARS-CoV-2 virus to invade our bodies and manifest infection, and ending with the recent long COVID, we are witnessing the evolving course of the disease in addition to the pandemic. Given the partially controlled course of the COVID-19 pandemic, the greatest challenge currently lies in managing the short- and long-term complications of COVID-19. We have assembled current knowledge of the broad spectrum of cardiovascular, pulmonary, and neuropsychiatric sequelae following SARS-CoV-2 infection to understand how these clinical manifestations collectively lead to a severe form of the disease. The ultimate goal would be to better understand these complications and find ways to prevent clinical deterioration.

Keywords: COVID-19; SARS-CoV-2; cardiovascular; complications; infection; inflammation; neuropsychiatric; pulmonary.

Publication types

Review

MeSH terms

COVID-19* / complications
Humans
Lung
Pandemics
Post-Acute COVID-19 Syndrome
SARS-CoV-2

Grants and funding

This research received no external funding.