The effectiveness of psychological interventions for anxiety in the perinatal period: A systematic review and meta-analysis

Psychol Psychother. 2023 Jun;96(2):296-327. doi: 10.1111/papt.12441. Epub 2022 Dec 11.

Abstract

Purpose: Anxiety disorders are relatively common during pregnancy and the postnatal period. Despite their potential acceptability to users, psychological interventions research for this population is still in its infancy. The meta-analysis aimed to comprehensively evaluate the evidence of the effectiveness of psychological interventions for reducing perinatal anxiety.

Method: The review followed PRISMA guidelines. A total of 26 studies published between 2004 and 2022 fulfilled inclusion criteria of which 22 were included in the meta-analysis.

Results: Results indicated that psychological interventions were more effective than control conditions in reducing symptoms of perinatal anxiety (equivalent to a medium post treatment effect size). Effect sizes were robust for cognitive, behavioural and mindfulness-based interventions. Targeting anxiety also appeared to impact on depression symptoms. There was substantial evidence of methodological heterogeneity.

Conclusions: This review demonstrates that psychological interventions are effective in reducing symptoms of both anxiety and comorbid anxiety and depression in both the antenatal and postnatal periods. Further research on longer-term effects, infant outcomes, treatment approach and modality are required.

Keywords: cognitive behavioural therapy; perinatal anxiety; postpartum; pregnancy; psychological interventions; psychological therapy.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Anxiety / psychology
  • Anxiety / therapy
  • Anxiety Disorders / psychology
  • Anxiety Disorders / therapy
  • Depression / psychology
  • Depression / therapy
  • Female
  • Humans
  • Mindfulness* / methods
  • Pregnancy
  • Psychosocial Intervention*