A case of chronic disseminated candidiasis in metamizole-induced neutropaenia

Infection. 2023 Jun;51(3):775-778. doi: 10.1007/s15010-022-01963-z. Epub 2022 Dec 14.

Abstract

Chronic disseminated candidiasis (CDC) is a severe complication of a disseminated yeast infection mainly seen after prolonged chemotherapy-induced neutropaenia in the context of haematological malignancy. We present a case of CDC in a patient with metamizole-induced neutropaenia. To the best of our knowledge, this is the first case described in this context. Furthermore, we highlight the role of steroids in the management of this disease.

Keywords: Chronic disseminated candidiasis; Corticosteroid therapy; Immune reconstitution inflammatory syndrome; Metamizole-induced neutropaenia.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candidiasis* / drug therapy
  • Chronic Disease
  • Dipyrone
  • Humans
  • Neutropenia* / complications
  • Retrospective Studies

Substances

  • Dipyrone
  • Antifungal Agents

Supplementary concepts

  • Systemic candidiasis