Recent progress in acute leukemia and myelodysplasia

Hetty E Carraway; Daniel A Pollyea; Eytan M Stein

doi:10.1016/j.beha.2022.101415

Recent progress in acute leukemia and myelodysplasia

Best Pract Res Clin Haematol. 2022 Dec;35(4):101415. doi: 10.1016/j.beha.2022.101415. Epub 2022 Nov 14.

Authors

Hetty E Carraway¹, Daniel A Pollyea², Eytan M Stein³

Affiliations

¹ Hematology Oncology Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: [email protected].
² Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO, USA. Electronic address: [email protected].
³ Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: [email protected].

PMID: 36517125
DOI: 10.1016/j.beha.2022.101415

Abstract

The advances and progress in the understanding and management of acute leukemia and myelodysplasia continue to occur at an exponential rate. While this has led to more therapy options, clinicians and researchers are now facing more challenges in terms of clinical decision-making and more unanswered questions. This paper has outlined some conundrums in acute leukemia and myelodysplasia, and the efforts that are underway to address these.

Keywords: ALL; AML; Acute lymphoblastic leukemia; Acute myeloid leukemia; MDS; Myelodysplasia; Myelodysplastic syndromes.

Publication types

Review

MeSH terms

Acute Disease
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Leukemia, Myeloid, Acute* / therapy
Myelodysplastic Syndromes* / diagnosis
Myelodysplastic Syndromes* / genetics
Myelodysplastic Syndromes* / therapy